Use with caution in patients with autoimmune conditions or those on systemic immunosuppressant drugs (discussion with specialist recommended) Local skin reactions are common, but rarely result in discontinuation of treatment For these reasons, podophyllotoxin has very limited utility for vulvovaginal wartsĪpply to affected area at bedtime 3 times per week (alternate days), wash off in the morningĬan be used for up to 16 weeks, although the majority who clear their warts will do so by 8 weeks Patients must be able to visualise, identify and reach their warts, as the solution must not come in contact with normal skin. Not for use in pregnancy (or if partner is pregnant) or breastfeeding - teratogenic This is the only treatment suitable in pregnancy.Īpply carefully to warts twice daily for 3 consecutive days, followed by 4 days rest each week, until warts have resolved, or for a maximum of 5 consecutive weeks 30% of patients will experience spontaneous clearance of warts over a 6-month period. For this reason recurrence is common, especially in the first 3 monthsĪn option for asymptomatic warts. The elimination of external visible warts may not decrease infectivity since the warts may not represent the entire viral burden.The goal of treatment is to eliminate warts that cause physical or psychological symptoms.Vaccination has reduced the prevalence of genital warts in younger age groups, and is recommended for those who are eligible, even if already sexually active.Gardasil 9 vaccination is funded for people aged 9-26 years, and protects against the types of HPV that cause most genital warts, as well as 7 types of oncogenic HPV. ![]() Vaccination provides effective long-term protection against HPV acquisition ![]() Previous infection does not necessarily create long-term immune memory, so may not prevent future infection with the same HPV type. Immunity from natural infection is poor.Because HPV infection may remain latent for some time, developing warts during a long-term relationship does not necessarily imply the presence of other sexual contacts HPV infection may become latent, and reactivate after several years, or infection may persist. Most HPV infection is transient and often becomes undetectable within 12 months. Most anogenital HPV infections are asymptomatic.Transmission is from skin-to-skin contact, and can occur through penetrative and non-penetrative sex, as well as sexual activity through fingers or sex toys from genital areas infected with HPV.It can be regarded as an inevitable consequence of being a sexually active adult HPV is almost universal among sexually active populations.These are low-risk types of HPV, which are generally not associated with malignancy 90% of genital warts are caused by HPV 6 or 11.HPV can be divided into low-risk and high-risk types, based on their association with the development of malignancy There are more than 100 types of HPV, with over 40 types which can infect the anogenital and oropharyngeal mucosa. ![]()
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